Atglistatin

Catalog No.: A13814

ATGL inhibitor

Atglistatin

Atglistatin Chemical Structure

CAS NO. 1469924-27-3

Atglistatin is a highly potent, selective and competitive inhibitor of adipose triglyceride lipase (ATGL) with an IC50 of ~0.7 μM for inhibition of lipolysis in vitro, but no toxicity up to a concentration of 50 μM.

Availability: In stock

Package Price Qty
10 mg
$126.00
25 mg
$252.00
50 mg
$378.00
100 mg
$630.00
10mM * 1mL in DMSO
$150.00
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Biological Activity

Atglistatin is a highly potent, selective and competitive inhibitor of adipose triglyceride lipase (ATGL) with an IC50 of ~0.7 μM for inhibition of lipolysis in vitro, but no toxicity up to a concentration of 50 μM.
In vitro DMSO 55 mg/mL (194.09 mM)
Water Insoluble
Ethanol 4 mg/mL (14.11 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.32 mL 176.58 mL 353.16 mL
0.5 mM 7.06 mL 35.32 mL 70.63 mL
1 mM 3.53 mL 17.66 mL 35.32 mL
5 mM 0.71 mL 3.53 mL 7.06 mL

*The above data is based on the productmolecular weight 283.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13814
Actions Inhibitor
CAS No. 1469924-27-3
Formula C17H21N3O
M. Wt 283.16
Purity >98%
SMILES CN(C)C1=CC=C(C=C1)C2=CC(=CC=C2)NC(=O)N(C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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