Atuveciclib (BAY-1143572)

Catalog No.: A16810
Selective PTEFb/CDK9 inhibitor
Atuveciclib, also known as BAY1143572, is a highly selective, potent and orally available inhibitor of PTEFb/CDK9 currently in Phase I.
Grouped product items
Product Name Price Stock Qty
Atuveciclib (BAY-1143572) 2mg
$120.00
In stock
Atuveciclib (BAY-1143572) 5mg
$220.00
In stock
Atuveciclib (BAY-1143572) 10mg
$380.00
In stock
Atuveciclib (BAY-1143572) 50mg
$1,200.00
In stock
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Adooq Products cited in reputable paper
Adooq's Atuveciclib (BAY-1143572) has been cited by 1 publications
  • Cole Schonhofer, .et al. , Biochem Pharmacol, 2021, Apr;186:114462 PMID: 33577894
  • Biological Activity
    Discription Atuveciclib, also known as BAY1143572, is a highly selective, potent and orally available inhibitor of PTEFb/CDK9 currently in Phase I.
    Targets
    Target Value
    Product Information
    Catalog Num A16810
    Formula C18H18FN5O2S
    Molecular Weight 387.43
    CAS Number 1414943-88-6
    SMILES O=S(C)(CC1=CC=CC(NC2=NC(C3=CC=C(F)C=C3OC)=NC=N2)=C1)=N
    Synonyms BAY 1143572, BAY-1143572
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 69 mg/mL (178.09 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.81 mL 129.06 mL 258.11 mL
    0.5 mM 5.16 mL 25.81 mL 51.62 mL
    1 mM 2.58 mL 12.91 mL 25.81 mL
    5 mM 0.52 mL 2.58 mL 5.16 mL
    Useful Calculator

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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