Atuveciclib (BAY-1143572)

Catalog No.: A16810

Selective PTEFb/CDK9 inhibitor

Atuveciclib (BAY-1143572)

Atuveciclib (BAY-1143572) Chemical Structure

CAS NO. 1414943-88-6

Atuveciclib, also known as BAY1143572, is a highly selective, potent and orally available inhibitor of PTEFb/CDK9 currently in Phase I.

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2 mg

Regular Price: $120.00

Special Price $96.00

5 mg

Regular Price: $220.00

Special Price $176.00

10 mg

Regular Price: $380.00

Special Price $304.00

50 mg

Regular Price: $1,200.00

Special Price $960.00

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Biological Activity

Atuveciclib, also known as BAY1143572, is a highly selective, potent and orally available inhibitor of PTEFb/CDK9 currently in Phase I.
In vitro DMSO 69 mg/mL (178.09 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.81 mL 129.06 mL 258.11 mL
0.5 mM 5.16 mL 25.81 mL 51.62 mL
1 mM 2.58 mL 12.91 mL 25.81 mL
5 mM 0.52 mL 2.58 mL 5.16 mL

*The above data is based on the productmolecular weight 387.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16810
Actions Inhibitor
CAS No. 1414943-88-6
Formula C18H18FN5O2S
M. Wt 387.43
Purity >98%
Synonyms BAY 1143572, BAY-1143572
SMILES O=S(C)(CC1=CC=CC(NC2=NC(C3=CC=C(F)C=C3OC)=NC=N2)=C1)=N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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