Aurora kinase-IN-2

Name: Aurora kinase-IN-2
Brand: Adooq Bioscience
SKU: A37434
Rating: 5 (288 reviews)

Catalog No.: A37434

Aurora Kinases Inhibitor

Aurora kinase-IN-2 is a potent inhibitor of Aurora kinases, demonstrating IC50 values of 90 nM for Aurora A and 152 nM for Aurora B. This compound effectively induces cell cycle arrest at the G2/M phase by modulating cyclin B1 and cdc2. It is primarily utilized in cancer research to explore the role of Aurora kinases in tumorigenesis and therapeutic response.

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Aurora kinase-IN-2 2241914-86-1 Aurora Kinases Inhibitor

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Grouped product items
Size	Price	Stock
25mg	$1,275.00	In stock
50mg	$1,625.00	In stock
100mg	$2,000.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	Aurora kinase-IN-2 is a potent inhibitor of Aurora kinases, demonstrating IC50 values of 90 nM for Aurora A and 152 nM for Aurora B. This compound effectively induces cell cycle arrest at the G2/M phase by modulating cyclin B1 and cdc2. It is primarily utilized in cancer research to explore the role of Aurora kinases in tumorigenesis and therapeutic response.

Product Information

Catalog Num	A37434
Formula	C22H18ClN5O3
Molecular Weight	435.86
CAS Number	2241914-86-1
SMILES	O=C(NC1=CC=CC(Cl)=C1)C2=CC=C(OC3=NC(C4=C(C)ON=C4C)=CN=C3N)C=C2

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