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Axareotide

Catalog No.: A63894
Somatostatin Analogue
Axareotide is a synthetic analogue of somatostatin that acts primarily on somatostatin receptors. It is known for its inhibitory effects on hormone secretion, particularly growth hormone and insulin. Axareotide is utilized in research focused on neuroendocrine tumors, acromegaly, and other conditions associated with abnormal hormone levels, providing valuable insights into somatostatin signaling pathways.
Axareotide 2126833-17-6 Somatostatin Analogue
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAxareotide is a synthetic analogue of somatostatin that acts primarily on somatostatin receptors. It is known for its inhibitory effects on hormone secretion, particularly growth hormone and insulin. Axareotide is utilized in research focused on neuroendocrine tumors, acromegaly, and other conditions associated with abnormal hormone levels, providing valuable insights into somatostatin signaling pathways.
Product Information
Catalog NumA63894
FormulaC54H68ClN11O12S2
Molecular Weight1162.77
CAS Number2126833-17-6
Sequence{4Cl-Phe}-{dCys}-Tyr-{4amide-dPhe}-{Nme-Lys}-Thr-Cys-{dTyr}-NH2 (disulfide bridge:Cys2-Cys7)
Sequence shortening{4Cl-Phe}-{dCys}-Y-{4amide-dPhe}-{Nme-Lys}-TC-{dTyr}-NH2 (disulfide bridge:Cys2-Cys7)
SMILESC([C@H]1NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](NC([C@H](CC3=CC=C(Cl)C=C3)N)=O)CSSC[C@@H](C(N[C@H](CC4=CC=C(O)C=C4)C(N)=O)=O)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CCCCNC)NC1=O)[H])C5=CC=C(C(N)=O)C=C5
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GPCR/G Protein > Somatostatin Receptors