Somatostatin Receptors

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  1. somatostatin receptor antagonist

    Octreotide is a peptide agonist for sst2, sst3 and sst5 somatostatin receptors. IC50/Kd values (nM) at cloned human somatostatin receptors are: 290 - 1140 (sst1), 0.4 - 2.1 (sst2), 4.4 - 34.5 (sst3), > 1000 (sst4), and 5.6 - 32 (sst5).
  2. Somatostatin is an endogenous peptide noted to inhibit the release of growth hormone, insulin and glucagon.
  3. somatostatin receptor 2 antagonist

    CYN-154806 is a potent selective somatostatin receptor 2 (sst2) antagonist.

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