AZD1080

Catalog No.: A12819

GSK3 inhibitor

AZD1080 Chemical Structure

CAS NO. 612487-72-6

AZD1080 is a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.

Availability: In stock

Package Price Qty
5 mg
$160.00
10 mg
$290.00
25 mg
$520.00
50 mg
$780.00
10mM * 1mL in DMSO
$206.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AZD1080 is a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.
Targets
GSK-3α GSK-3β
6.9 nM31 nM
In vitro (25°C) DMSO 52 mg/mL (155.51 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Catalog Num A12819
Actions Inhibitor
M. Wt N/A
Formula N/A
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 612487-72-6
Synonyms AZD 1080, AZD-1080
SMILES C1COCCN1CC2=CN/C(=C\3/C4=C(C=CC(=C4)C#N)NC3=O)/C=C2

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