AZD1080

Catalog No.: A12819

GSK3 inhibitor

AZD1080

AZD1080 Chemical Structure

CAS NO. 612487-72-6

AZD1080 is a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.

Availability: In stock

Package Price Qty
5 mg
$160.00
10 mg
$290.00
25 mg
$520.00
50 mg
$780.00
10mM * 1mL in DMSO
$206.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Shengzhong Liu, .et al. STAT1-avtiviated LINC00961 regulates myocardial infarction by the PI3K/AKT/GSK3?? signaling pathway, J Cell Biochem, 2019, 2019

Biological Activity

AZD1080 is a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.
Targets
GSK-3α GSK-3β
6.9 nM31 nM
In vitro (25°C) DMSO 52 mg/mL (155.51 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.9 mL 149.52 mL 299.04 mL
0.5 mM 5.98 mL 29.9 mL 59.81 mL
1 mM 2.99 mL 14.95 mL 29.9 mL
5 mM 0.6 mL 2.99 mL 5.98 mL

*The above data is based on the productmolecular weight 334.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12819
Actions Inhibitor
M. Wt 334.4
Formula C19H18N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 612487-72-6
Synonyms AZD 1080, AZD-1080
SMILES C1COCCN1CC2=CN/C(=C\3/C4=C(C=CC(=C4)C#N)NC3=O)/C=C2

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy AZD1080 | AZD1080 Supplier | purchase | cost | manufacturer | order | distributor | buy 612487-72-6| 612487-72-6 Supplier | purchase 612487-72-6 | 612487-72-6 cost | 612487-72-6 manufacturer | order 612487-72-6 | 612487-72-6 distributor
Rewards