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Biological Activity
Azelnidipine is a calcium blocker that attenuates liver fibrosis and may increase antioxidant defence. that attenuates liver fibrosis and may increase antioxidant defence.
Targets
| Calcium channel | ||||
| In vitro (25°C) | DMSO | 115 mg/mL (197.37 mM) | |
| Water | Insoluble | ||
| Ethanol | 7 mg/mL (12.01 mM) | ||
| In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.16 mL | 85.81 mL | 171.61 mL |
| 0.5 mM | 3.43 mL | 17.16 mL | 34.32 mL |
| 1 mM | 1.72 mL | 8.58 mL | 17.16 mL |
| 5 mM | 0.34 mL | 1.72 mL | 3.43 mL |
*The above data is based on the productmolecular weight 582.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11219 |
|---|---|
| Actions | Blocker |
| CAS No. | 123524-52-7 |
| Formula | C33H34N4O6 |
| M. Wt | 582.7 |
| Purity | >98% |
| SMILES | CC1=C(C(C(=C(N1)N)C(=O)OC2CN(C2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC(C)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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