Azido-PEG1-C2-methylamine is a PEG-based linker specifically designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features an azide functionality, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. Its versatile click chemistry properties make it an invaluable tool in targeted protein degradation research and the development of innovative therapeutic strategies.
Azido-PEG1-C2-methylamine is a PEG-based linker specifically designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features an azide functionality, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. Its versatile click chemistry properties make it an invaluable tool in targeted protein degradation research and the development of innovative therapeutic strategies.
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