Azido-PEG1-CH2CO2-NHS is an alkyl/ether-based PROTAC linker that facilitates the synthesis of PROTAC molecules. This click chemistry reagent features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing compounds. Additionally, it is compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) reactions involving DBCO or BCN groups, making it valuable for advanced chemical biology applications. Its utility in constructing targeted protein degradation systems enhances its relevance in molecular biology research.
Azido-PEG1-CH2CO2-NHS is an alkyl/ether-based PROTAC linker that facilitates the synthesis of PROTAC molecules. This click chemistry reagent features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing compounds. Additionally, it is compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) reactions involving DBCO or BCN groups, making it valuable for advanced chemical biology applications. Its utility in constructing targeted protein degradation systems enhances its relevance in molecular biology research.
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