Azido-PEG11-amine is a PEG-based PROTAC linker that facilitates the synthesis of targeted protein degraders. This molecule features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing compounds. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules that contain dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups. Its versatile reactivity makes it a valuable tool for bioconjugation and drug discovery applications.
Azido-PEG11-amine is a PEG-based PROTAC linker that facilitates the synthesis of targeted protein degraders. This molecule features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing compounds. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules that contain dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups. Its versatile reactivity makes it a valuable tool for bioconjugation and drug discovery applications.
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