Azido-PEG16-acid is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). Featuring an azide functional group, this compound is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with DBCO or BCN moieties. This reagent is essential for facilitating the precise assembly of PROTACs, contributing to advancements in targeted protein degradation research.
Azido-PEG16-acid is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). Featuring an azide functional group, this compound is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with DBCO or BCN moieties. This reagent is essential for facilitating the precise assembly of PROTACs, contributing to advancements in targeted protein degradation research.
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