Azido-PEG2-C1-Boc is a versatile PEG-based linker designed for PROTAC synthesis, utilizing its azide functionality for click chemistry applications. This compound participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkynes and can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. Its efficient conjugation capabilities make it a valuable tool for researchers focusing on targeted protein degradation and protein interaction studies.
Azido-PEG2-C1-Boc is a versatile PEG-based linker designed for PROTAC synthesis, utilizing its azide functionality for click chemistry applications. This compound participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkynes and can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. Its efficient conjugation capabilities make it a valuable tool for researchers focusing on targeted protein degradation and protein interaction studies.
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