Azido-PEG2-CH2COOH is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). Featuring an azide group, it participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules or DBCO/BCN derivatives, enhancing the selective targeting of proteins for degradation. This versatile linker facilitates the development of novel targeted protein degradation strategies, making it valuable for chemical biology and drug discovery research applications.
Azido-PEG2-CH2COOH is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). Featuring an azide group, it participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules or DBCO/BCN derivatives, enhancing the selective targeting of proteins for degradation. This versatile linker facilitates the development of novel targeted protein degradation strategies, making it valuable for chemical biology and drug discovery research applications.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
