Azido-PEG2-propargyl

Catalog No.: A82681
PROTAC Linker
Azido-PEG2-propargyl is a PEG-based PROTAC linker that facilitates the construction of PROTAC molecules. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing partners. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-modified compounds. Azido-PEG2-propargyl is essential for researchers aiming to develop targeted protein degradation systems.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAzido-PEG2-propargyl is a PEG-based PROTAC linker that facilitates the construction of PROTAC molecules. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing partners. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-modified compounds. Azido-PEG2-propargyl is essential for researchers aiming to develop targeted protein degradation systems.
Product Information
Catalog NumA82681
FormulaC7H11N3O2
Molecular Weight169.18
CAS Number1245006-63-6
SMILESC#CCOCCOCCN=[N+]=[N-]
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