Azido-PEG3-C-Boc is a PEG-based linker specifically designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). It features an azide functional group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing compounds. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN derivatives, facilitating efficient conjugation in chemical biology applications. This reagent is suitable for researchers investigating targeted protein degradation mechanisms and advancing drug discovery efforts.
Azido-PEG3-C-Boc is a PEG-based linker specifically designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). It features an azide functional group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing compounds. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN derivatives, facilitating efficient conjugation in chemical biology applications. This reagent is suitable for researchers investigating targeted protein degradation mechanisms and advancing drug discovery efforts.
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