Azido-PEG3-methyl ester is a PEG-based linker designed for PROTAC synthesis. This compound features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-modified targets. Its efficient reactivity makes it a valuable tool for developing targeted protein degradation strategies in chemical biology research.
Azido-PEG3-methyl ester is a PEG-based linker designed for PROTAC synthesis. This compound features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-modified targets. Its efficient reactivity makes it a valuable tool for developing targeted protein degradation strategies in chemical biology research.
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