Azido-PEG3-S-PEG4-t-butyl ester serves as a versatile PEG-based linker for the synthesis of PROTACs, facilitating targeted protein degradation. Featuring an azide functional group, this compound is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN moieties, making it valuable for applications in chemical biology and therapeutic development.
Azido-PEG3-S-PEG4-t-butyl ester serves as a versatile PEG-based linker for the synthesis of PROTACs, facilitating targeted protein degradation. Featuring an azide functional group, this compound is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN moieties, making it valuable for applications in chemical biology and therapeutic development.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
