Azido-PEG3-Sulfone-PEG4-acid is a PEG-based linker specifically designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features an azide group that enables its application in click chemistry, allowing for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing compounds. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions when combined with DBCO or BCN groups, making it a versatile tool in chemical biology and drug development research.
Azido-PEG3-Sulfone-PEG4-acid is a PEG-based linker specifically designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features an azide group that enables its application in click chemistry, allowing for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing compounds. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions when combined with DBCO or BCN groups, making it a versatile tool in chemical biology and drug development research.
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