Azido-PEG35-amine is a PEG-based linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras), facilitating targeted protein degradation. This compound features an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups, making it a versatile tool for chemical biology applications and the development of novel therapeutics.
Azido-PEG35-amine is a PEG-based linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras), facilitating targeted protein degradation. This compound features an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups, making it a versatile tool for chemical biology applications and the development of novel therapeutics.
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