Azido-PEG36-alcohol is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis targeting chimeras). This compound features an azide functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with substrates containing DBCO or BCN groups, making it suitable for various chemical biology applications, including targeted protein degradation studies.
Azido-PEG36-alcohol is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis targeting chimeras). This compound features an azide functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with substrates containing DBCO or BCN groups, making it suitable for various chemical biology applications, including targeted protein degradation studies.
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