Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane is a PEG-based linker designed for the synthesis of PROTACs (proteolysis targeting chimeras). This compound features an azide functional group that enables its participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups, facilitating the development of complex bioconjugates. It is an essential reagent for researchers engaged in targeted protein degradation studies.
Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane is a PEG-based linker designed for the synthesis of PROTACs (proteolysis targeting chimeras). This compound features an azide functional group that enables its participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups, facilitating the development of complex bioconjugates. It is an essential reagent for researchers engaged in targeted protein degradation studies.
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