Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a PEG-based PROTAC linker that facilitates the development of targeted protein degradation strategies. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing substrates, including those with DBCO or BCN groups. Its versatility makes it suitable for various applications in chemical biology and drug discovery.
Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a PEG-based PROTAC linker that facilitates the development of targeted protein degradation strategies. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing substrates, including those with DBCO or BCN groups. Its versatility makes it suitable for various applications in chemical biology and drug discovery.
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