Azido-PEG4-Amido-Tris is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). It features an azide functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as strain-promoted azide-alkyne cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. This versatility makes Azido-PEG4-Amido-Tris a valuable tool for researchers developing targeted protein degradation strategies.
Azido-PEG4-Amido-Tris is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). It features an azide functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as strain-promoted azide-alkyne cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. This versatility makes Azido-PEG4-Amido-Tris a valuable tool for researchers developing targeted protein degradation strategies.
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