Azido-PEG4-tetra-Ac-beta-D-glucose serves as a versatile PROTAC linker by enabling the synthesis of proteolysis-targeting chimeras (PROTACs). Its azide functionality facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. This compound's distinct properties make it valuable for developing targeted degradation strategies in chemical biology research.
Azido-PEG4-tetra-Ac-beta-D-glucose serves as a versatile PROTAC linker by enabling the synthesis of proteolysis-targeting chimeras (PROTACs). Its azide functionality facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. This compound's distinct properties make it valuable for developing targeted degradation strategies in chemical biology research.
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