Azido-PEG5-CH2CO2-NHS is a PEG-based linker designed for use in the synthesis of PROTACs through click chemistry. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkynes and molecules containing DBCO or BCN moieties. Its unique properties make it a valuable tool for researchers in protein degradation studies and other chemical biology applications.
Azido-PEG5-CH2CO2-NHS is a PEG-based linker designed for use in the synthesis of PROTACs through click chemistry. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkynes and molecules containing DBCO or BCN moieties. Its unique properties make it a valuable tool for researchers in protein degradation studies and other chemical biology applications.
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