Azido-PEG5-CH2CO2-PFP is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules or those carrying DBCO/BCN groups. Its robust reactivity makes it an essential tool for advancing research in targeted protein degradation.
Azido-PEG5-CH2CO2-PFP is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules or those carrying DBCO/BCN groups. Its robust reactivity makes it an essential tool for advancing research in targeted protein degradation.
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