Azido-PEG8-CH2COO-PFP

Catalog No.: A82658
PROTAC Linkers
Azido-PEG8-CH2COO-PFP is a PEGylated PROTAC linker designed to facilitate the synthesis of targeted protein degraders. Functioning as a click chemistry reagent, it features an azide group that engages in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) reactions involving DBCO or BCN groups. This compound is essential for researchers focused on developing novel therapeutic strategies through protein modulation.
Grouped product items
Size Price Stock Qty
2mg
$40.00
In stock
5mg
$60.00
In stock
50mg
$180.00
In stock
100mg
$280.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAzido-PEG8-CH2COO-PFP is a PEGylated PROTAC linker designed to facilitate the synthesis of targeted protein degraders. Functioning as a click chemistry reagent, it features an azide group that engages in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) reactions involving DBCO or BCN groups. This compound is essential for researchers focused on developing novel therapeutic strategies through protein modulation.
Product Information
Catalog NumA82658
FormulaC24H34F5N3O10
Molecular Weight619.53
CAS Number2182601-80-3
SMILESO=C(OC1=C(F)C(F)=C(F)C(F)=C1F)COCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2