AZSMO-23 is a potent activator of the hERG K+ channel, demonstrating effective modulation of wild-type hERG pre-pulse and tail currents with EC50 values of 28.6 µM and 11.2 µM, respectively. This compound is particularly relevant for studies investigating long QT syndrome, offering insights into cardiac repolarization and related disorders. Researchers can utilize AZSMO-23 to explore the therapeutic potential and underlying mechanisms of hERG channel dysfunction.
AZSMO-23 is a potent activator of the hERG K+ channel, demonstrating effective modulation of wild-type hERG pre-pulse and tail currents with EC50 values of 28.6 µM and 11.2 µM, respectively. This compound is particularly relevant for studies investigating long QT syndrome, offering insights into cardiac repolarization and related disorders. Researchers can utilize AZSMO-23 to explore the therapeutic potential and underlying mechanisms of hERG channel dysfunction.
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