β-catenin-IN-8 is a potent inhibitor of β-catenin, targeting the Wnt signaling pathway. This compound effectively reduces the levels of β-catenin and c-Myc proteins, leading to downregulation of Wnt-target genes such as Fgf20 and Sall4. β-catenin-IN-8 exhibits anti-cancer activity in colorectal cancer models and demonstrates favorable metabolic stability, making it a valuable tool for research into cancer biology and therapeutic strategies.
β-catenin-IN-8 is a potent inhibitor of β-catenin, targeting the Wnt signaling pathway. This compound effectively reduces the levels of β-catenin and c-Myc proteins, leading to downregulation of Wnt-target genes such as Fgf20 and Sall4. β-catenin-IN-8 exhibits anti-cancer activity in colorectal cancer models and demonstrates favorable metabolic stability, making it a valuable tool for research into cancer biology and therapeutic strategies.
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