BAF312 (Siponimod)

Catalog No.: A12906

S1PR1/S1PR5 inhibitor

BAF312 (Siponimod)

BAF312 (Siponimod) Chemical Structure

CAS NO. 1230487-00-9

BAF312 is a next-generation potent sphingosine 1-phosphate (S1P) receptor agonist, selective for S1P1 and S1P5.

Availability: In stock

Package Price Qty
2 mg

Regular Price: $40.00

Special Price $32.00

5 mg

Regular Price: $55.00

Special Price $44.00

10 mg

Regular Price: $80.00

Special Price $64.00

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Biological Activity

BAF312 is a next-generation potent sphingosine 1-phosphate (S1P) receptor agonist, selective for S1P1 and S1P5.
In vitro DMSO Warmed: 99 mg/mL (191.63 mM)
Water Insoluble
Ethanol Warmed: 44 mg/mL (85.17 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.36 mL 96.79 mL 193.57 mL
0.5 mM 3.87 mL 19.36 mL 38.71 mL
1 mM 1.94 mL 9.68 mL 19.36 mL
5 mM 0.39 mL 1.94 mL 3.87 mL

*The above data is based on the productmolecular weight 516.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12906
Actions Inhibitor
CAS No. 1230487-00-9
Formula C29H35F3N2O3
M. Wt 516.6
Purity >98%
Synonyms Siponimod
SMILES CCC1=C(C=CC(=C1)C(=NOCC2=CC(=C(C=C2)C3CCCCC3)C(F)(F)F)C)CN4CC(C4)C(=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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