Bardoxolone (CDDO)

Name: Bardoxolone (CDDO)
SKU: A11324
Price: 110 USD
Rating: 5 (2 reviews)

Catalog No.: A11324

IκB/IKK inhibitor

Adooq's Bardoxolone (CDDO) has been cited by 2 publications

Bardoxolone methyl, previously known as RTA 402, is the lead molecule in Reata's portfolio of Antioxidant Inflammation Modulators (AIMs).

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Grouped product items
Product Name	Price	Stock
Bardoxolone (CDDO) 10mg	$110.00	In stock
Bardoxolone (CDDO) 25mg	$220.00	In stock
Bardoxolone (CDDO) 50mg	$330.00	In stock
Bardoxolone (CDDO) 100mg	$540.00	In stock

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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper

Adooq's Bardoxolone (CDDO) has been cited by 2 publications

Rothan HA, .et al. , Antiviral Res, 2019, Aug 14;171:104590 PMID: 31421166

Turpaev K, .et al. , Eur J Pharmacol, 2016, Aug 5;784:69-80 PMID: 27178899

Biological Activity

Discription	Bardoxolone methyl, previously known as RTA 402, is the lead molecule in Reata's portfolio of Antioxidant Inflammation Modulators (AIMs).

Chemical Information

Catalog Num	A11324
Formula	C31H41NO4
Molecular Weight	491.66
CAS Number	218600-44-3
SMILES	C[C@@]12CC[C@]3(CCC(C[C@H]3[C@H]1C(=O)C=C4[C@]2(CC[C@@H]5[C@@]4(C=C(C(=O)C5(C)C)C#N)C)C)(C)C)C(=O)O
Synonyms	RTA 401, Bardoxolone
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	5 mg/mL (10.17 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.34 mL	101.7 mL	203.39 mL
0.5 mM	4.07 mL	20.34 mL	40.68 mL
1 mM	2.03 mL	10.17 mL	20.34 mL
5 mM	0.41 mL	2.03 mL	4.07 mL

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂