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- Turpaev K,et al. Aromatic malononitriles stimulate the resistance of insulin-producing beta-cells to oxidants and inflammatory cytokines, Eur J Pharmacol, 2016, Aug 5;784:69-80 27178899
|Storage||at -20°C 3 years Powder|
|Synonyms||RTA 401, Bardoxolone|
|SMILES code||C[[email protected]@]12CC[[email protected]]3(CCC(C[[email protected]]3[[email protected]]1C(=O)C=C4[[email protected]]2(CC[[email protected]@H]5[[email protected]@]4(C=C(C(=O)C5(C)C)C#N)C)C)(C)C)C(=O)O|
|Chemical Name||2-Cyano-3,12-dioxooleana-1,9-dien-28-oic acid|
|Bardoxolone methyl, previously known as RTA 402, is the lead molecule in Reata's portfolio of Antioxidant Inflammation Modulators (AIMs).|
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||20.34 mL||101.7 mL||203.39mL|
|0.5 mM||4.07 mL||20.34 mL||40.68 mL|
|1 mM||2.03 mL||10.17 mL||20.34 mL|
|5 mM||0.41 mL||2.03 mL||4.07 mL|
*The above data is based on the productmolecular weight 491.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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