Total item
Cart Subtotal
$0.00 Biological Activity
Batimastat (BB-94) is a potent and synthetic inhibitor of a broad spectrum of matrix metalloproteinases (MMPs), including interstitial collagenase (IC50 = 3 nM), stromelysin (IC50 = 20 nM), Mr 72,000 type IV collagenase (IC50 = 4 nM), Mr 92,000 type IV collagenase (IC50 = 4 nM), and matrilysin (IC50 = 6 nM). It is a low-molecular-weight (MW = 478) and peptide-like collagen substrate analogue consisting of a peptide backbone and a hydroxamic acid group which bind to MMPs and the catalytically active zinc atom respectively.
Targets
| MMP-1 | MMP-2 | MMP-9 | MMP-7 | MMP-3 |
| 3 nM | 4 nM | 4 nM | 6 nM | 20 nM |
| In vitro (25°C) | DMSO | 84 mg/mL (175.86 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 2% DMSO+40% PEG 300+2% Tween 80+ddH2O | 1 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.94 mL | 104.68 mL | 209.36 mL |
| 0.5 mM | 4.19 mL | 20.94 mL | 41.87 mL |
| 1 mM | 2.09 mL | 10.47 mL | 20.94 mL |
| 5 mM | 0.42 mL | 2.09 mL | 4.19 mL |
*The above data is based on the productmolecular weight 477.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12985 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 130370-60-4 |
| Formula | C23H31N3O4S2 |
| M. Wt | 477.64 |
| Purity | >98% |
| Synonyms | BB 94 |
| SMILES | CC(C)C[[email protected]]([[email protected]](CSC1=CC=CS1)C(=O)NO)C(=O)N[[email protected]@H](CC2=CC=CC=C2)C(=O)NC |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Datasheet
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy Batimastat (BB-94) | Batimastat (BB-94) Supplier | purchase | cost | manufacturer | order | distributor | buy 130370-60-4| 130370-60-4 Supplier | purchase 130370-60-4 | 130370-60-4 cost | 130370-60-4 manufacturer | order 130370-60-4 | 130370-60-4 distributor
Adooq Quality Guarantee
We promise all products perform as described.