Batimastat (BB-94)

Catalog No.: A12985

MMP inhibitor

Batimastat (BB-94)

Batimastat (BB-94) Chemical Structure

CAS NO. 130370-60-4

Batimastat (BB-94) is a potent and synthetic inhibitor of a broad spectrum of matrix metalloproteinases (MMPs), including interstitial collagenase (IC50 = 3 nM), stromelysin (IC50 = 20 nM), Mr 72,000 type IV collagenase (IC50 = 4 nM), Mr 92,000 type IV collagenase (IC50 = 4 nM), and matrilysin (IC50 = 6 nM). It is a low-molecular-weight (MW = 478) and peptide-like collagen substrate analogue consisting of a peptide backbone and a hydroxamic acid group which bind to MMPs and the catalytically active zinc atom respectively.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $90.00

Special Price $72.00

10 mg

Regular Price: $140.00

Special Price $112.00

25 mg

Regular Price: $240.00

Special Price $192.00

50 mg

Regular Price: $380.00

Special Price $304.00

10mM * 1mL in DMSO
$145.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

Batimastat (BB-94) is a potent and synthetic inhibitor of a broad spectrum of matrix metalloproteinases (MMPs), including interstitial collagenase (IC50 = 3 nM), stromelysin (IC50 = 20 nM), Mr 72,000 type IV collagenase (IC50 = 4 nM), Mr 92,000 type IV collagenase (IC50 = 4 nM), and matrilysin (IC50 = 6 nM). It is a low-molecular-weight (MW = 478) and peptide-like collagen substrate analogue consisting of a peptide backbone and a hydroxamic acid group which bind to MMPs and the catalytically active zinc atom respectively.
Targets
MMP-1 MMP-2 MMP-9 MMP-7 MMP-3
3 nM4 nM4 nM6 nM20 nM
In vitro (25°C) DMSO 96 mg/mL (200.98 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.94 mL 104.68 mL 209.36 mL
0.5 mM 4.19 mL 20.94 mL 41.87 mL
1 mM 2.09 mL 10.47 mL 20.94 mL
5 mM 0.42 mL 2.09 mL 4.19 mL

*The above data is based on the productmolecular weight 477.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A12985
Actions Inhibitor
M. Wt 477.64
Formula C23H31N3O4S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 130370-60-4
Synonyms BB 94
SMILES CC(C)C[[email protected]]([[email protected]](CSC1=CC=CS1)C(=O)NO)C(=O)N[[email protected]@H](CC2=CC=CC=C2)C(=O)NC

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Batimastat (BB-94) | Batimastat (BB-94) Supplier | purchase Batimastat (BB-94) | Batimastat (BB-94) cost | Batimastat (BB-94) manufacturer | order Batimastat (BB-94) | Batimastat (BB-94) distributor | buy 130370-60-4| 130370-60-4 Supplier | purchase 130370-60-4 | 130370-60-4 cost | 130370-60-4 manufacturer | order 130370-60-4 | 130370-60-4 distributor
Rewards