BAY-298 is a selective luteinizing hormone receptor (LH-R) antagonist with an IC50 of 96 nM for human LH, 23 nM for rat LH, and 78 nM for cynomolgus monkey LH. This orally active compound effectively reduces sex hormone levels, making it a valuable tool for research focused on reproductive biology and endocrine regulation. Its specificity and potency position BAY-298 as a critical reagent for studies investigating LH-R signaling pathways and potential therapeutic applications in hormone-related disorders.
BAY-298 is a selective luteinizing hormone receptor (LH-R) antagonist with an IC50 of 96 nM for human LH, 23 nM for rat LH, and 78 nM for cynomolgus monkey LH. This orally active compound effectively reduces sex hormone levels, making it a valuable tool for research focused on reproductive biology and endocrine regulation. Its specificity and potency position BAY-298 as a critical reagent for studies investigating LH-R signaling pathways and potential therapeutic applications in hormone-related disorders.
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