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BC-05

Catalog No.: A77337
CD13 and Proteasome Inhibitors
BC-05 is a potent inhibitor of CD13 and the 20S proteasome, exhibiting an IC50 of 0.13 μM for human CD13 and 1.39 μM for the proteasome. This compound is orally active and serves as a valuable tool in the investigation of multiple myeloma and related hematological malignancies. Its dual-targeting mechanism makes BC-05 a significant reagent for elucidating pathways involved in cancer progression and therapeutic resistance.
BC-05 2260717-73-3 CD13 and Proteasome Inhibitors
Grouped product items
Size Price Stock Qty
5mg
$1,155.00
In stock
10mg
$1,225.00
In stock
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBC-05 is a potent inhibitor of CD13 and the 20S proteasome, exhibiting an IC50 of 0.13 μM for human CD13 and 1.39 μM for the proteasome. This compound is orally active and serves as a valuable tool in the investigation of multiple myeloma and related hematological malignancies. Its dual-targeting mechanism makes BC-05 a significant reagent for elucidating pathways involved in cancer progression and therapeutic resistance.
Product Information
Catalog NumA77337
FormulaC21H29BN2O9
Molecular Weight464.27
CAS Number2260717-73-3
SMILESO=C(N[C@@H](CC(C)C)B1OC(C(CC(O)=O)(CC(O)=O)O1)=O)[C@@H](O)[C@H](N)CC2=CC=CC=C2
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Proteases > Proteasome