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Catalog No.: A14381

beta-catenin inhibitor


BC2059 Chemical Structure

CAS NO. 1227637-23-1

BC2059 is an orally bioavailable and potent beta-catenin inhibitor.

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10 mg
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Ji-Hye Jung, .et al. CXCR2 Inhibition in Human Pluripotent Stem Cells Induces Predominant Differentiation to Mesoderm and Endoderm Through Repression of mTOR, β-Catenin, and hTERT Activities, Stem Cells Dev, 2016, Jul 1; 25(13): 1006-1019 PMID: 27188501

Biological Activity

BC2059 is an orally bioavailable and potent beta-catenin inhibitor.
In vitro DMSO 88 mg/mL
Water 88 mg/mL
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.99 mL 84.93 mL 169.85 mL
0.5 mM 3.4 mL 16.99 mL 33.97 mL
1 mM 1.7 mL 8.49 mL 16.99 mL
5 mM 0.34 mL 1.7 mL 3.4 mL

*The above data is based on the productmolecular weight 588.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14381
Actions Inhibitor
CAS No. 1227637-23-1
Formula C28H36N4O6S2
M. Wt 588.74
Purity >98%
Synonyms BC-2059, BC 2059
SMILES O=S(C1=CC2=C(C=C1)/C(C3=CC=C(S(=O)(N4C[[email protected]](C)C[[email protected]](C)C4)=O)C=C3/C2=N\O)=N\O)(N5C[[email protected]](C)C[[email protected]](C)C5)=O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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