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- Ji-Hye Jung, .et al. CXCR2 Inhibition in Human Pluripotent Stem Cells Induces Predominant Differentiation to Mesoderm and Endoderm Through Repression of mTOR, β-Catenin, and hTERT Activities, Stem Cells Dev, 2016, Jul 1; 25(13): 1006-1019 PMID: 27188501
Biological Activity
BC2059 is an orally bioavailable and potent beta-catenin inhibitor.
| In vitro | DMSO | 88 mg/mL | |
| Water | 88 mg/mL | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.99 mL | 84.93 mL | 169.85 mL |
| 0.5 mM | 3.4 mL | 16.99 mL | 33.97 mL |
| 1 mM | 1.7 mL | 8.49 mL | 16.99 mL |
| 5 mM | 0.34 mL | 1.7 mL | 3.4 mL |
*The above data is based on the productmolecular weight 588.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14381 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1227637-23-1 |
| Formula | C28H36N4O6S2 |
| M. Wt | 588.74 |
| Purity | >98% |
| Synonyms | BC-2059, BC 2059 |
| SMILES | O=S(C1=CC2=C(C=C1)/C(C3=CC=C(S(=O)(N4C[[email protected]](C)C[[email protected]](C)C4)=O)C=C3/C2=N\O)=N\O)(N5C[[email protected]](C)C[[email protected]](C)C5)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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