Benz-AP is a potent photosensitizer that generates singlet oxygen, exhibiting a negative correlation with human carboxylesterase 2 (hCES2) activity. This compound demonstrates enhanced photocytotoxicity in cancer cells, particularly in environments with low hCES2 levels. Upon two-photon excitation (TPE), Benz-AP produces reactive oxygen species (ROS), effectively inducing cell death in cancer cells and tumor spheroids, making it a valuable tool for cancer research applications.
Benz-AP is a potent photosensitizer that generates singlet oxygen, exhibiting a negative correlation with human carboxylesterase 2 (hCES2) activity. This compound demonstrates enhanced photocytotoxicity in cancer cells, particularly in environments with low hCES2 levels. Upon two-photon excitation (TPE), Benz-AP produces reactive oxygen species (ROS), effectively inducing cell death in cancer cells and tumor spheroids, making it a valuable tool for cancer research applications.
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