Benzyl 4-((2-aminoethoxy)methyl)piperidine-1-carboxylate

Catalog No.: A84443
PROTAC Linker
Benzyl 4-((2-aminoethoxy)methyl)piperidine-1-carboxylate is a PROTAC linker essential for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of targeted protein degradation strategies by linking target proteins to E3 ligases, enhancing selective degradation pathways. Research applications include cellular studies investigating protein dynamics and the therapeutic potential of targeted degradation in various diseases.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBenzyl 4-((2-aminoethoxy)methyl)piperidine-1-carboxylate is a PROTAC linker essential for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of targeted protein degradation strategies by linking target proteins to E3 ligases, enhancing selective degradation pathways. Research applications include cellular studies investigating protein dynamics and the therapeutic potential of targeted degradation in various diseases.
Product Information
Catalog NumA84443
FormulaC16H24N2O3
Molecular Weight292.38
CAS Number1353961-56-4
SMILESO=C(OCC=1C=CC=CC1)N2CCC(COCCN)CC2
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