Benzyl-PEG4-Azido is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimera (PROTAC) compounds. This reagent features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. The versatility of Benzyl-PEG4-Azido makes it an essential component for researchers employing PROTAC technology to modulate protein degradation pathways in biochemical studies.
Benzyl-PEG4-Azido is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimera (PROTAC) compounds. This reagent features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. The versatility of Benzyl-PEG4-Azido makes it an essential component for researchers employing PROTAC technology to modulate protein degradation pathways in biochemical studies.
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