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Biological Activity
Betrixaban is an anticoagulant drug which acts as a direct factor Xa inhibitor. It is potent, orally active and highly selective for factor Xa, being selected from a group of similar compounds for its low hERG affinity.
| In vitro | DMSO | 32 mg/mL (70.8 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.13 mL | 110.64 mL | 221.28 mL |
| 0.5 mM | 4.43 mL | 22.13 mL | 44.26 mL |
| 1 mM | 2.21 mL | 11.06 mL | 22.13 mL |
| 5 mM | 0.44 mL | 2.21 mL | 4.43 mL |
*The above data is based on the productmolecular weight 451.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12518 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 330942-05-7 |
| Formula | C23H22ClN5O3 |
| M. Wt | 451.91 |
| Purity | >98% |
| Synonyms | PRT-054,021, PRT-054021 |
| SMILES | CN(C)C(=N)C1=CC=C(C=C1)C(=O)NC2=C(C=C(C=C2)OC)C(=O)NC3=NC=C(C=C3)Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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