BI-78D3

Catalog No.: A13683

JNK inhibitor

BI-78D3 Chemical Structure

CAS NO. 883065-90-5

BI-78D3 is a competitive JNK (c-Jun N-terminal kinases) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. BI 78D3 inhibits JIP1(JNK interacting protein 1)-JNK binding (IC50 = 500 nM).

Availability: In stock

Package Price Qty
10 mg
$120.00
25 mg
$250.00
50 mg
$400.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

BI-78D3 is a competitive JNK (c-Jun N-terminal kinases) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. BI 78D3 inhibits JIP1(JNK interacting protein 1)-JNK binding (IC50 = 500 nM).
Targets
JNK
280 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.39 mL 131.93 mL 263.85 mL
0.5 mM 5.28 mL 26.39 mL 52.77 mL
1 mM 2.64 mL 13.19 mL 26.39 mL
5 mM 0.53 mL 2.64 mL 5.28 mL

*The above data is based on the productmolecular weight 379. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13683
Actions Inhibitor
M. Wt 379
Formula C13H9N5O5S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 883065-90-5
Synonyms BI 78D3, BI78D3
SMILES C1COC2=C(O1)C=CC(=C2)N3C(=O)NN=C3SC4=NC=C(S4)[N+](=O)[O-]

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