BI-78D3

Catalog No.: A13683

JNK inhibitor

BI-78D3

BI-78D3 Chemical Structure

CAS NO. 883065-90-5

BI-78D3 is a competitive JNK (c-Jun N-terminal kinases) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. BI 78D3 inhibits JIP1(JNK interacting protein 1)-JNK binding (IC50 = 500 nM).

Availability: In stock

Package Price Qty
10 mg
$120.00
25 mg
$250.00
50 mg
$400.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

BI-78D3 is a competitive JNK (c-Jun N-terminal kinases) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. BI 78D3 inhibits JIP1(JNK interacting protein 1)-JNK binding (IC50 = 500 nM).
Targets
JNK
280 nM
In vitro DMSO 89 mg/mL (234.6 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.39 mL 131.93 mL 263.85 mL
0.5 mM 5.28 mL 26.39 mL 52.77 mL
1 mM 2.64 mL 13.19 mL 26.39 mL
5 mM 0.53 mL 2.64 mL 5.28 mL

*The above data is based on the productmolecular weight 379. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13683
Actions Inhibitor
CAS No. 883065-90-5
Formula C13H9N5O5S2
M. Wt 379
Purity >98%
Synonyms BI 78D3, BI78D3
SMILES C1COC2=C(O1)C=CC(=C2)N3C(=O)NN=C3SC4=NC=C(S4)[N+](=O)[O-]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy BI-78D3 | BI-78D3 Supplier | purchase | cost | manufacturer | order | distributor | buy 883065-90-5| 883065-90-5 Supplier | purchase 883065-90-5 | 883065-90-5 cost | 883065-90-5 manufacturer | order 883065-90-5 | 883065-90-5 distributor
Rewards