BIBR 953 (Dabigatran, Pradaxa)

Catalog No.: A10138

Thrombin inhibitor

BIBR 953 (Dabigatran, Pradaxa)

BIBR 953 (Dabigatran, Pradaxa) Chemical Structure

CAS NO. 211914-51-1

BIBR 953 (Dabigatran, Pradaxa) is a highly selective, reversible, and potent thrombin inhibitor and is orally available as the prodrug, dabigatran etexilate. It has shown antithrombotic efficacy in animal models of thrombosis, with a rapid onset of action and predictable pharmacodynamic response.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $80.00

Special Price $72.00

10 mg

Regular Price: $140.00

Special Price $126.00

50 mg

Regular Price: $450.00

Special Price $405.00

100 mg

Regular Price: $720.00

Special Price $648.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

BIBR 953 (Dabigatran, Pradaxa) is a highly selective, reversible, and potent thrombin inhibitor and is orally available as the prodrug, dabigatran etexilate. It has shown antithrombotic efficacy in animal models of thrombosis, with a rapid onset of action and predictable pharmacodynamic response.

Targets
Thrombin (Cell-free assay)
9.3 nM
In vitro DMSO 0.5 mg/mL (1.06 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.21 mL 106.04 mL 212.09 mL
0.5 mM 4.24 mL 21.21 mL 42.42 mL
1 mM 2.12 mL 10.6 mL 21.21 mL
5 mM 0.42 mL 2.12 mL 4.24 mL

*The above data is based on the productmolecular weight 471.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10138
Actions Inhibitor
M. Wt 471.5
Formula C25H25N7O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 211914-51-1
Synonyms BIBR-953, BIBR953
SMILES CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy BIBR 953 (Dabigatran, Pradaxa) | BIBR 953 (Dabigatran, Pradaxa) Supplier | purchase BIBR 953 (Dabigatran, Pradaxa) | BIBR 953 (Dabigatran, Pradaxa) cost | BIBR 953 (Dabigatran, Pradaxa) manufacturer | order BIBR 953 (Dabigatran, Pradaxa) | BIBR 953 (Dabigatran, Pradaxa) distributor | buy 211914-51-1| 211914-51-1 Supplier | purchase 211914-51-1 | 211914-51-1 cost | 211914-51-1 manufacturer | order 211914-51-1 | 211914-51-1 distributor
Rewards