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Dabigatran etexilate mesylate

Catalog No.: A15057

direct thrombin inhibitor

Dabigatran etexilate mesylate

Dabigatran etexilate mesylate Chemical Structure

CAS NO. 872728-81-9

Dabigatran etexilate mesylate is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM.

Availability: In stock

Package Price Qty
5 mg
$50.00
10 mg
$70.00
50 mg
$90.00
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Biological Activity

Dabigatran etexilate mesylate is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.82 mL 69.08 mL 138.15 mL
0.5 mM 2.76 mL 13.82 mL 27.63 mL
1 mM 1.38 mL 6.91 mL 13.82 mL
5 mM 0.28 mL 1.38 mL 2.76 mL

*The above data is based on the productmolecular weight 723.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15057
Actions Inhibitor
CAS No. 872728-81-9
Formula C35H45N7O8S
M. Wt 723.84
Purity >98%
Synonyms Pradaxa, BIBR 1048MS, Dabigatran etexilate methanesulfonate
SMILES CCCCCCOC(=O)N=C(C1=CC=C(C=C1)NCC2=NC3=C(N2C)C=CC(=C3)C(=O)N(CCC(=O)OCC)C4=CC=CC=N4)N.CS(=O)(=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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