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Biological Activity
Dabigatran etexilate mesylate is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.82 mL | 69.08 mL | 138.15 mL |
| 0.5 mM | 2.76 mL | 13.82 mL | 27.63 mL |
| 1 mM | 1.38 mL | 6.91 mL | 13.82 mL |
| 5 mM | 0.28 mL | 1.38 mL | 2.76 mL |
*The above data is based on the productmolecular weight 723.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15057 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 872728-81-9 |
| Formula | C35H45N7O8S |
| M. Wt | 723.84 |
| Purity | >98% |
| Synonyms | Pradaxa, BIBR 1048MS, Dabigatran etexilate methanesulfonate |
| SMILES | CCCCCCOC(=O)N=C(C1=CC=C(C=C1)NCC2=NC3=C(N2C)C=CC(=C3)C(=O)N(CCC(=O)OCC)C4=CC=CC=N4)N.CS(=O)(=O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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