Bicyclo[2.2.2]octane-1,4-dicarboxylic acid serves as a essential PROTAC linker in the development of proteolysis-targeting chimeras. This compound facilitates the assembly of targeted protein degradation systems by connecting E3 ligase and protein of interest, promoting efficient ubiquitination and subsequent proteasomal degradation. Its application is particularly valuable in drug discovery and molecular biology research focused on targeted protein modulation.
Bicyclo[2.2.2]octane-1,4-dicarboxylic acid serves as a essential PROTAC linker in the development of proteolysis-targeting chimeras. This compound facilitates the assembly of targeted protein degradation systems by connecting E3 ligase and protein of interest, promoting efficient ubiquitination and subsequent proteasomal degradation. Its application is particularly valuable in drug discovery and molecular biology research focused on targeted protein modulation.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula: