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BIM-23190

Catalog No.: A63891
SSTR Agonist
BIM-23190 is a somatostatin analog that selectively targets somatostatin receptor subtype 2 (SSTR2) and subtype 5 (SSTR5), exhibiting Ki values of 0.34 nM and 11.1 nM, respectively. This compound acts as an agonist, demonstrating significant biological activity in modulating neuroendocrine functions. BIM-23190 is applicable in research areas related to cancer and acromegaly, making it a valuable tool for studying somatostatin signaling pathways and therapeutic interventions.
BIM-23190 182153-96-4 SSTR Agonist
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5mg
$795.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBIM-23190 is a somatostatin analog that selectively targets somatostatin receptor subtype 2 (SSTR2) and subtype 5 (SSTR5), exhibiting Ki values of 0.34 nM and 11.1 nM, respectively. This compound acts as an agonist, demonstrating significant biological activity in modulating neuroendocrine functions. BIM-23190 is applicable in research areas related to cancer and acromegaly, making it a valuable tool for studying somatostatin signaling pathways and therapeutic interventions.
Product Information
Catalog NumA63891
FormulaC57H79N13O12S2
Molecular Weight1202.45
CAS Number182153-96-4
Sequence{4-(2-Hydroxyethyl)-1-piperazinylacetyl}-{D-Phe}-Cys-Tyr-{D-Trp}-Lys-{Abu}-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys7)
Sequence shortening{4-(2-Hydroxyethyl)-1-piperazinylacetyl}-{D-Phe}-CY-{D-Trp}-K-{Abu}-CT-NH2 (Disulfide bridge: Cys2-Cys7)
SMILESCC[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@@H](Cc1ccccc1)NC(=O)CN1CCN(CCO)CC1
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GPCR/G Protein > Somatostatin Receptors