Biotin-PEG6-Thalidomide

Catalog No.: A31045
PROTAC Linkers
Biotin-PEG6-Thalidomide serves as a PEG-based PROTAC linker, instrumental in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound enhances the delivery and cellular penetration of targeted proteins for ubiquitination and subsequent degradation. Its unique design facilitates the exploration of protein modulation in various biological contexts and therapeutic applications, making it an essential tool for researchers investigating targeted protein degradation processes.
Grouped product items
Size Price Stock Qty
5mg
$285.00
In stock
10mg
$495.00
In stock
25mg
$740.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBiotin-PEG6-Thalidomide serves as a PEG-based PROTAC linker, instrumental in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound enhances the delivery and cellular penetration of targeted proteins for ubiquitination and subsequent degradation. Its unique design facilitates the exploration of protein modulation in various biological contexts and therapeutic applications, making it an essential tool for researchers investigating targeted protein degradation processes.
Product Information
Catalog NumA31045
FormulaC37H53N5O12S
Molecular Weight791.91
CAS Number2144775-48-2
SMILESO=C(NCCOCCOCCOCCOCCOCCOCCN1C(C(N(C(C2=C3C=CC=C2)=O)C3=O)CCC1=O)=O)CCCC[C@H]4SC[C@@]([C@@]4([H])N5)([H])NC5=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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