Biphalin TFA

Catalog No.: A62485
Opioid Peptide
Biphalin TFA is a potent opioid peptide analog designed for effective interaction with opioid receptors, demonstrating a dual enkephalin pharmacophore structure that facilitates blood-brain barrier penetration. This compound exhibits significant analgesic properties in various pain models, including acute, neuropathic, and chronic settings. Additionally, Biphalin TFA has been shown to possess antiviral, antiproliferative, anti-inflammatory, and neuroprotective activities, making it a valuable tool for research in pain management and related therapeutic areas.
Grouped product items
Size Price Stock Qty
5mg
$350.00
In stock
10mg
$650.00
In stock
50mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBiphalin TFA is a potent opioid peptide analog designed for effective interaction with opioid receptors, demonstrating a dual enkephalin pharmacophore structure that facilitates blood-brain barrier penetration. This compound exhibits significant analgesic properties in various pain models, including acute, neuropathic, and chronic settings. Additionally, Biphalin TFA has been shown to possess antiviral, antiproliferative, anti-inflammatory, and neuroprotective activities, making it a valuable tool for research in pain management and related therapeutic areas.
Product Information
Catalog NumA62485
FormulaC46H56N10O10·xC2HF3O2
Molecular Weight909.00 (free base)
CAS Number126872-95-5
SequenceTyr-{dAla}-Gly-Phe-NH2 (covalent bridge:Phe-Phe, dimer)
Sequence shorteningY-{D-Ala}-GF-NH2 (covalent bridge:Phe-Phe, dimer)
SMILESC(C(O)=O)(F)(F)F.[C@H](CC1=CC=CC=C1)(C(NNC([C@H](CC2=CC=CC=C2)NC(CNC([C@H](NC([C@H](CC3=CC=C(O)C=C3)N)=O)C)=O)=O)=O)=O)NC(CNC([C@H](NC([C@H](CC4=CC=C(O)C=C4)N)=O)C)=O)=O
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