Bis-Mal-Lysine-PEG4-acid is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound allows for the conjugation of E3 ligase recruiters to target proteins, facilitating the targeted degradation of specific proteins via the ubiquitin-proteasome system. It is a valuable tool for researchers investigating protein function and cellular pathways, as well as developing novel therapeutic approaches.
Bis-Mal-Lysine-PEG4-acid is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound allows for the conjugation of E3 ligase recruiters to target proteins, facilitating the targeted degradation of specific proteins via the ubiquitin-proteasome system. It is a valuable tool for researchers investigating protein function and cellular pathways, as well as developing novel therapeutic approaches.
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