Bis-PEG13-acid is a polyethylene glycol (PEG)-based linker specifically designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of targeting moieties to E3 ligase ligands, enabling targeted protein degradation. Its application is crucial in the development of new therapeutic agents that harness the ubiquitin-proteasome system for selective protein modulation in various biological research fields.
Bis-PEG13-acid is a polyethylene glycol (PEG)-based linker specifically designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of targeting moieties to E3 ligase ligands, enabling targeted protein degradation. Its application is crucial in the development of new therapeutic agents that harness the ubiquitin-proteasome system for selective protein modulation in various biological research fields.
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