Bis-PEG7-t-butyl ester

Catalog No.: A83017
PROTAC Linkers
Bis-PEG7-t-butyl ester is a polyethylene glycol (PEG)-based linker designed for use in PROTAC (proteolysis targeting chimera) synthesis. This compound facilitates the development of novel PROTACs by providing a flexible and soluble linker that enhances target protein degradation. It is valuable in drug discovery and development research, particularly in studies focused on targeted protein modulation and therapeutic strategies.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBis-PEG7-t-butyl ester is a polyethylene glycol (PEG)-based linker designed for use in PROTAC (proteolysis targeting chimera) synthesis. This compound facilitates the development of novel PROTACs by providing a flexible and soluble linker that enhances target protein degradation. It is valuable in drug discovery and development research, particularly in studies focused on targeted protein modulation and therapeutic strategies.
Product Information
Catalog NumA83017
FormulaC24H46O10
Molecular Weight494.62
CAS Number2702251-39-4
SMILESCC(C)(C)OC(CCOCCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O)=O
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