BLT2 antagonist-1 is a selective antagonist of the BLT2 receptor, demonstrated to inhibit the chemotaxis of CHO-BLT2 cells with an IC50 of 224 nM, while showing no effect on CHO-BLT1 cells. It also effectively inhibits the binding of leukotriene B4 (LTB4) to the BLT2 receptor, with a Ki value of 132 nM. This compound is valuable for research into inflammatory airway diseases, including asthma and chronic obstructive pulmonary disease (COPD).
BLT2 antagonist-1 is a selective antagonist of the BLT2 receptor, demonstrated to inhibit the chemotaxis of CHO-BLT2 cells with an IC50 of 224 nM, while showing no effect on CHO-BLT1 cells. It also effectively inhibits the binding of leukotriene B4 (LTB4) to the BLT2 receptor, with a Ki value of 132 nM. This compound is valuable for research into inflammatory airway diseases, including asthma and chronic obstructive pulmonary disease (COPD).
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